About A. Untergasser

I am a molecular biologist. I studied biology in Heidelberg in Germany from 1996-2000. I made my PhD from 2000-2002. Afterwards I made a first PostDoc in Cologne and a second in Wageningen, the Netherlands. Since 2009 I teach biology and chemistry at a high school in Michelstadt and continue the bioinformatics work at the ZMBH at Heidelberg University and the EMBL.

Publications:

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Tica J, Lee E, Untergasser A, Meiers S, Garfield DA, Gokcumen O, Furlong EE, Park PJ, Stütz AM, Korbel JO.
Next-generation sequencing-based detection of germline L1-mediated transductions.
in BMC Genomics. 2016 May 10;17:342. doi: 10.1186/s12864-016-2670-x.

Ruijter JM, Ruiz Villalba A, Hellemans J, Untergasser A, van den Hoff MJ.
Removal of between-run variation in a multi-plate qPCR experiment.
in Biomol Detect Quantif. 2015 Jul 30;5:10-4. doi: 10.1016/j.bdq.2015.07.001. eCollection 2015 Sep.

Sudmant PH, Rausch T, Gardner EJ, Handsaker RE, Abyzov A, Huddleston J, Zhang Y, Ye K, Jun G, Fritz MH, Konkel MK, Malhotra A, Stütz AM, Shi X, Casale FP, Chen J, Hormozdiari F, Dayama G, Chen K, Malig M, Chaisson MJP, Walter K, Meiers S, Kashin S, Garrison E, Auton A, Lam HYK, Mu XJ, Alkan C, Antaki D, Bae T, Cerveira E, Chines P, Chong Z, Clarke L, Dal E, Ding L, Emery S, Fan X, Gujral M, Kahveci F, Kidd JM, Kong Y, Lameijer EW, McCarthy S, Flicek P, Gibbs RA, Marth G, Mason CE, Menelaou A, Muzny DM, Nelson BJ, Noor A, Parrish NF, Pendleton M, Quitadamo A, Raeder B, Schadt EE, Romanovitch M, Schlattl A, Sebra R, Shabalin AA, Untergasser A, Walker JA, Wang M, Yu F, Zhang C, Zhang J, Zheng-Bradley X, Zhou W, Zichner T, Sebat J, Batzer MA, McCarroll SA; 1000 Genomes Project Consortium, Mills RE, Gerstein MB, Bashir A, Stegle O, Devine SE, Lee C, Eichler EE, Korbel JO.
An integrated map of structural variation in 2,504 human genomes.
in Nature. 2015 Oct 1;526(7571):75-81. doi: 10.1038/nature15394.

Ruijter JM, Lefever S, Anckaert J, Hellemans J, Pfaffl MW, Benes V, Bustin SA, Vandesompele J, Untergasser A; RDML consortium.
RDML-Ninja and RDMLdb for standardized exchange of qPCR data.
in BMC Bioinformatics. 2015 Jun 20;16:197. doi: 10.1186/s12859-015-0637-6.

Untergasser A, Cutcutache I, Koressaar T, Ye J, Faircloth BC, Remm M, Rozen SG.
Primer3--new capabilities and interfaces.
in Nucleic Acids Res. 2012 Aug 1;40(15):e115. Epub 2012 Jun 22.

Untergasser A, Bijl GJ, Liu W, Bisseling T, Schaart JG and Geurts R.
One-step Agrobacterium mediated transformation of eight genes essential for rhizobium symbiotic signaling using the novel binary vector system pHUGE.
in PLoS One. 2012;7(10):e47885.

Op den Camp R, Streng A, De Mita S, Cao Q, Polone E, Liu W, Ammiraju JS, Kudrna D, Wing R, Untergasser A, Bisseling T, Geurts R.
LysM-Type Mycorrhizal Receptor Recruited for Rhizobium Symbiosis in Nonlegume Parasponia.
in Science. 2011 Feb 18;331(6019):909-12. doi: 10.1126/science.1198181.

John von Freyend M, Untergasser A, Arzberger S, Oberwinkler H, Drebber U, Schirmacher P, Protzer U.
Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B.
in J Viral Hepat. 2011 Mar;18(3):216-26. doi: 10.1111/j.1365-2893.2010.01302.x.

Kettner C, Field D, Sansone S, Taylor C, Aerts J, Binns N, Black A, Britten CM, de Marco A, Fostel J, Gaudet P, Gonzalez-Beltran A, Hardy N, Hellmans J, Hermjakob H, Juty N, Leebens-Mack J, Maguire E, Neumann S, Orchard S, Parkinson H, Piel W, Ranganathan S, Rocca-Serra P, Santarsiero A, Shotton D, Peter Sterk P, Untergasser A, Whetzel PL.
Meeting Report from the Second "Minimum Information for Biological and Biomedical Investigations" (MIBBI) workshop.
in Stand Genomic Sci. 2010 Dec 25;3(3):259-66.

Untergasser A, Bisseling T and Geurts R.
Chapter: Making Rhizobium-Infected Root Nodules.
in Prokaryotic Symbionts in Plants, Series: Microbiology Monographs, Vol. 8, Pawlowski, Katharina (Ed.) 2009, ISBN: 978-3-540-75459-6

Lefever S, Hellemans J, Pattyn F, Przybylski DR, Taylor C, Geurts R, Untergasser A, Vandesompele J; RDML consortium.
RDML: structured language and reporting guidelines for real-time quantitative PCR data.
Nucleic Acids Res. 2009 Apr;37(7):2065-9. Epub 2009 Feb 17.

Taylor CF, Field D, Sansone SA, Aerts J, Apweiler R, Ashburner M, Ball CA, Binz PA, Bogue M, Booth T, Brazma A, Brinkman RR, Michael Clark A, Deutsch EW, Fiehn O, Fostel J, Ghazal P, Gibson F, Gray T, Grimes G, Hancock JM, Hardy NW, Hermjakob H, Julian RK Jr, Kane M, Kettner C, Kinsinger C, Kolker E, Kuiper M, Le Novère N, Leebens-Mack J, Lewis SE, Lord P, Mallon AM, Marthandan N, Masuya H, McNally R, Mehrle A, Morrison N, Orchard S, Quackenbush J, Reecy JM, Robertson DG, Rocca-Serra P, Rodriguez H, Rosenfelder H, Santoyo-Lopez J, Scheuermann RH, Schober D, Smith B, Snape J, Stoeckert CJ Jr, Tipton K, Sterk P, Untergasser A, Vandesompele J, Wiemann S.
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project.
Nat Biotechnol. 2008 Aug;26(8):889-96.

Cullimore J, Lefebvre B, Arrighi JF, Gough C, Barre A, Bono JJ, Rougé P, Samain E, Driguez H, Imberty A, Untergasser A, Geurts R, Gadella TWJ, Cañada J, Jimenez-Barbero J.
Chapter: Nod-Factor Perception in Medicago truncatula.
in Current Plant Science and Biotechnology in Agriculture. Biological Nitrogen Fixation: Towards Poverty Alleviation through Sustainable Agriculture. Volume 42, 2008, pp 167-171.

Untergasser A, Lefever S, Pattyn F, Hellemans J, Vandesompele J.
A new standard for qPCR data: RDML.
European Biotechnology News, Issue 03-04/2008. (No peer-review)

Untergasser A, Lefever S, Pattyn F, Hellemans J, Vandesompele J.
PCR-Standardisierung: RDML - neuer Standard für qPCR-Daten.
Laborwelt, Nr.2/2008, 9. Jahrgang. (No peer-review).

Untergasser A, Nijveen H, Rao X, Bisseling T, Geurts R, Leunissen JA.
Primer3Plus, an enhanced web interface to Primer3.
Nucleic Acids Res. 2007 Jul;35(Web Server issue):W71-4. Epub 2007 May 7.

Ganten TM, Koschny R, Sykora J, Schulze-Bergkamen H, Buchler P, Haas TL, Schader MB, Untergasser A, Stremmel W, Walczak H.
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs.
Clin Cancer Res. 2006 Apr 15;12(8):2640-6.

Untergasser A, Zedler U, Langenkamp A, Hosel M, Quasdorff M, Esser K, Dienes HP, Tappertzhofen B, Kolanus W, Protzer U.
Dendritic cells take up viral antigens but do not support the early steps of hepatitis B virus infection.
Hepatology. 2006 Mar;43(3):539-47.

Shin EC, Protzer U, Untergasser A, Feinstone SM, Rice CM, Hasselschwert D, Rehermann B.
Liver-directed gamma interferon gene delivery in chronic hepatitis C.
J Virol. 2005 Nov;79(21):13412-20.

Oberwinkler H, Untergasser A, Sprinzl M, Protzer U
Transfer of HBV Genomes into Mice.
von Weizsäcker F, Roggendorf M (eds): Models of Viral Hepatitis.
Monogr Virol. Basel, Karger, 2005, vol 25, pp 33-41. (DOI: 10.1159/000084318)

Untergasser A, Protzer U.
Hepatitis B virus-based vectors allow the elimination of viral gene expression and the insertion of foreign promoters.
Hum Gene Ther. 2004 Feb;15(2):203-10.

Schulze-Bergkamen H, Untergasser A, Dax A, Vogel H, Buchler P, Klar E, Lehnert T, Friess H, Buchler MW, Kirschfink M, Stremmel W, Krammer PH, Muller M, Protzer U.
Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection.
J Hepatol. 2003 Jun;38(6):736-44.

Untergasser A.
Rekombinante Hepatitis B Viren-Vektoren als Werkzeuge für Molekularbiologie und Therapie : Optimierung eines Systems
Dissertation : Universität Heidelberg, Fakultät für Biowissenschaften, 2003.